Scientists are describing a plant compound called Salvestrols as one of the most significant breakthroughs in nutritional science since the discovery of vitamins.
Salvestrols are naturally occurring compounds (phytonutrients) which fight fungi in fruit and vegetables, are essential for human wellbeing and are being hailed as having a significantly powerful impact on fighting disease.
Salvestrols were discovered by Professor Gerry Potter, Professor of Medicinal Chemistry and Director of the Cancer Drug Discovery Group at Leicester’s De Montfort University and Professor Dan Burke, a pharmacologist and former Dean of Science at the UK’s Sunderland University.
Professor Potter had spent almost 20 years designing synthetic cancer drugs and discovered that plants have similar compounds that could prove beneficial in the treatment of diseased cells in humans.
Salvestrols emerged out of a cancer drug discovery programme which has delivered several key pharmaceutical products (including Abirateronea, a breakthrough treatment for prostate cancer).
Salvestrols’ effect on humans has since been backed by other prominent scientists. Case studies on diseased patients who have used Salvestrols with positive outcomes have been published in respected medical journals.
South African medical practitioners and patients are also increasingly discovering the incredibly positive effects of Salvestrols on disease.
During his research, Prof Burke discovered that diseased cells contain a unique enzyme protein called CYP1B1. He found that Salvestrols have a deadly effect on this enzyme while leaving healthy cells intact.
In collaboration with Prof Potter, they discovered that Salvestrols exert similar effects to those they were seeking through synthetic pharmaceuticals. As a result, their focus and research is now entirely dedicated to Salvestrols.
Potter then coined the name Salvestrols from the Latin word salve, meaning ‘to save’ and Burke has described Salvestrols as “probably the most significant breakthrough in nutrition since the discovery of vitamins”.
More than $30 million has gone into the research of Salvestrols over the last 15 years and Salvestrols food supplements are now available worldwide including Europe, Australia, the UK, Canada, Japan and now in Southern Africa.
Salvestrols are found in the skin of fruit and vegetables but due to modern farming practices — in particular the use of fungicides – their levels have diminished in commercially produced crops. Organic fruit and vegetables have a higher salvestrol content.
Salvestrols was voted as “the no 1 big idea of the year” in health by Dr John Briffa (www.drbriffa.com) in the Observer Magazine. He wrote in the Observer newspaper that Salvestrols could play a key role in cancer research.
The British Daily Mail dedicated an article to Salvestrols and quoted the results of research by Burke and Potter which were published in the British Naturopathic Journal.
Various other studies relating to Salvestrols have been undertaken over the last two decades. Below are the most prominent with case studies to be found in point 2:
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by Dr Mark Hyman
Sourced on June 27th, 2013 from http://drhyman.com/blog/2013/06/27/5-clues-you-are-addicted-to-sugar/#lightbox/0/
Debate has raged recently about whether junk food, the hyper-processed, hyper-palatable food that has become our SAD (standard American diet) is addictive in the same way that heroin or cocaine is addictive. A new study published in theAmerican Journal of Clinical Nutrition suggests that, in fact, higher sugar, higher glycemic foods can be addictive.
David Ludwig, author of Ending the Food Fight, and his colleagues at Harvard, in a very sophisticated study, showed that foods with more sugar, foods that raise blood sugar even more than table sugar such as white flour, white potatoes and refined starch have what is called a high glycemic index, trigger a special region in the brain called the nucleus accumbens that is known to be “ground zero” for conventional addiction, such as gambling or drug abuse.
I stopped by CBS This Morning recently to talk about this groundbreaking study. Watch the interview here.
It appears part of the reason almost 70 percent of Americans are overweight or one in two Americans has pre-diabetes or Type 2 diabetes may not be gluttony, lack of willpower or absence of personal responsibility but plain old, garden variety biological addiction.
Many previous studies have shown how this region of brain, the pleasure center, lights up in response to images or eating sugary, processed or junk food. But many of these studies used very different foods as a comparison. If you compare cheesecake to boiled vegetables, there are many reasons the pleasure center can light up. It tastes better or it looks better. This is interesting data, but it’s not hard proof of addiction.
This new study took on the hard job of proving the biology of sugar addiction. The researchers did a randomized, blinded, crossover study using the most rigorous research design to ward off any criticism (which will inevitably come from the $1 trillion food industry).
They took 12 overweight or obese men between the ages of 18 and 35 and gave each a low sugar or low glycemic index (37 percent) milkshake, and then, four hours later, they measured the activity of the brain region (nucleus accumbens) that controls addiction. They also measured blood sugar and hunger.
Then, days later, they had them back for another milkshake. But this time they switched the milkshakes. They were designed to taste exactly the same and be exactly the same in every way except in how much and how quickly it spiked blood sugar. The second milkshake was designed to be high in sugar with a high glycemic index (84 percent). The shakes had exactly the same amount of calories, protein, fat and carbohydrate. Think of it as a trick milkshake. The participants didn’t know which milkshake they were getting, and their mouth couldn’t tell the difference, but their brains could.
Each participant received a brain scan and blood tests for glucose and insulin after each version of the milkshake. They were their own control group. Without exception, they all had the same response. The high sugar or glycemic index milkshake caused a spike in blood sugar and insulin and an increase in reported hunger and cravings four hours after the shake. Remember — exactly the same calories, sweetness, texture and macronutrient content.
This finding was not surprising and has been shown many times before.
But the breakthrough finding was this: When the high glycemic shake was consumed, the nucleus accumbens lit up like a Christmas tree. This pattern occurred in every single participant and was statistically significant.
This study showed two things.
First, the body responds quite differently to different calories, even if the protein, fat and carbs (and taste) are exactly the same.
And second, foods that spike blood sugar are biologically addictive.
This game-changing study must force a shift in the conversation about obesity in America. There are 600,000 processed foods in the marketplace, 80 percent of which have added hidden sugar. The average American consumes 22 teaspoons of sugar a day, mostly hidden, and the average teenage boy has 34 teaspoons a day (more than two 20 ounce sodas). One serving of Prego tomato sauce has more sugar than a serving of Oreo cookies. Sweetened yogurts can have more sugar than a can of soda.
Sugar is the core ingredient used by the food industry to make bad ingredients (processed flour and chemicals) taste good. Our consumption has increased from 10 pounds per person in 1800 to 140 pounds per person per year today.
Each year, the average American also consumes 133 pounds of white or wheat flour, which raises blood sugar more than table sugar (sucrose).
When a 12-year-old boy needs a liver transplant after a steady diet of soda and white flour, or when a 2-year-old can’t walk because he is too fat at 50 pounds, we can no longer point to personal responsibility as the solution to our obesity epidemic.
What if Kobe Bryant or LeBron James went on national television promoting the benefits of “cocaine water” to increase sports performance? Would you allow heroin dispensers in your kid’s school? Think heroin lollipops or morphine muffins. This is exactly what’s happening in America today.
No one wants to be fat or become a drug addict. No one wants their life destroyed by disability and illness. We have policies and laws that protect people from alcohol, tobacco and illegal drugs of abuse. Sugar and flour (and too much starchy white potatoes and white rice) or products containing them appear to be no different. In fact, some animal studies show that sugar is eight times as addictive as cocaine.
It is time to stop blaming the fat person. Can we really blame our children if we freely give them drugs of abuse in the school lunch line or as after school snacks? Can we really blame the average overweight person? The nutritional landscape in America is a food carnival.
Kelly Brownell from Yale’s Rudd Center for Food Policy and Obesity has created a validated food questionnaire to help you determine if you are a food addict. He recently also published a textbook, Food and Addiction, that lays out the science of how our hyper-processed, hyper-palatable, hyper-sweet industrial food has hijacked our brain chemistry and biology.
Here are five clues you may be addicted to sugar, flour and processed food:
There are resources to help you break your food addiction and stop the cravings.
Now, I would love to hear from you.
Have you experienced uncontrollable cravings for sugar and refined foods?
How has it affected your life?
Have you blamed yourself for your behavior?
Do you think we should change food policy to protect children from marketing of foods proven to be addictive?